Over time, the skin undergoes clinical and histological changes due to intrinsic aging (chronoaging), Chronoaging can be worsened by cumulative environmental damage, such as the chronic ultraviolet light exposure (photodamage), the presence of pollutants, and smoking. The superimposed effects of photodamage on intrinsically aging skin ha ve been termed photoaging, this is characterized by wrinkles, shallowness, laxity, mottled pigmentation, and rough textured skin.